Importance of Vascular Function in Patients with Heart Failure with Preserved Ejection Fraction
نویسندگان
چکیده
There had been no effective cardioprotective medications for heart failure with preserved ejection fraction (HFpEF). Therefore, treatment intervention at the hypertension (HT) stage (stage A), which is a major factor in HFpEF, necessary. In fact, SPRINT and STEP trials reported that strict intensive blood pressure (BP) control was useful, reducing approximately 25% of primary endpoints, including cardiovascular events. The effectiveness BP reduction HFpEF after onset HF C or D) has shown to generally follow J-curve phenomenon. Both left ventricular systolic/diastolic dysfunction vascular are related pathophysiology HF. case coexisting failure, lowering effective, because it decreases afterload. However, increase incidence renal dysfunction; therefore, paying attention degree association multiple organs when determining target important consider. decision on optimal choice cardioprotective/antihypertensive should be based pathologic condition.
منابع مشابه
Hospitalisation in Patients With Heart Failure With Preserved Ejection Fraction
Heart failure is highly prevalent with more than 50% of cases being patients with a preserved ejection fraction (HFPEF), a figure that is projected to increase due to the changing risk factor landscape, in particular the ageing population. Overall mortality is similar to patients with heart failure with reduced ejection fraction (HFREF), as are the rates of hospitalisation. Patients with HFPEF ...
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Symptomatic heart failure, despite preserved left ventricular (LV) ejection fraction, is a well-recognized phenomenon. This manifestation of diastolic dysfunction is associated with increased morbidity and mortality and can be attributed to a variety of pathogeneses, including diabetes mellitus, hypertension, infiltrative processes, and obesity. Unlike in systolic heart failure, where LV ejecti...
متن کاملHeart Failure with Preserved Ejection Fraction
1. Demonstrate the association between heart failure with preserved ejection fraction (HFpEF) and survival. 2. Given a patient with heart failure (HF), recognize HFpEF on the basis of clinical signs and symptoms, physical examination, echocardiography, and radiographic findings. 3. Classify patients at high risk of hospitalization and mortality through assessing risk factors, clinical presentat...
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ژورنال
عنوان ژورنال: Medical research archives
سال: 2022
ISSN: ['2375-1916', '2375-1924']
DOI: https://doi.org/10.18103/mra.v10i5.2791